Day 26 🧪 Welcome back to 30 Days of ASCP: Make It Make Sense because once you get it, you never forget it. Antibody panels look overwhelming until you realize they’re not about memorizing antibodies: they’re about pattern recognition. You’re comparing reactions across cells to determine which antigens are present and which antibodies can be ruled in or out. Homozygous cells react stronger, heterozygous cells may show weaker reactions, and non-reactive cells help you exclude possibilities. Once

Welcome back to 30 Days of ASCP: Make It Make Sense Series, because once you get it, you never forget it. Day 1/30: Today is World AIDS Day, so let’s break down how someone is actually diagnosed with AIDS from the laboratory perspective. A person is first screened for HIV using a 4th-generation antigen/antibody test, which detects HIV-1, HIV-2, and the p24 antigen. If that test is positive, we move to an HIV-1/HIV-2 differentiation assay to determine which virus is present. If that result comes

Day 9 🧪 Welcome back to 30 Days of ASCP: Make It Make Sense, because once you get it, you never forget it. Elution and adsorption are both used to separate antibodies from red blood cells, but they serve different purposes. Elution is used when an antibody is already attached to the patient’s red cells; we strip it off to identify what that antibody is, which is especially important in cases like positive DATs or hemolytic disease of the newborn. Adsorption is used when antibodies are free in t

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