Base and nucleotide excision repair (BER and NER) pathways are normally associated with removal of specific types of DNA damage: small base modifications (such as those induced by DNA oxidation) and ...
The Summit supercomputer revealed how damaged strands of DNA are surgically repaired by a molecular pathway called nucleotide excision repair, or NER. NER’s protein components can change shape to ...
The Summit supercomputer revealed how damaged strands of DNA are surgically repaired by a molecular pathway called nucleotide excision repair, or NER. NER’s protein components can change shape to ...
Abstract: Nucleotide excision repair (NER) is a key mechanism in cellular damage repair, and therefore in the cell's response to cisplatin treatment in neoplastic diseases. In this paper we suggest a ...
Atherosclerotic plaques demonstrate extensive accumulation of oxidative DNA damage, predominantly as 8-oxoguanine (8oxoG) lesions. 8oxoG is repaired by base excision repair enzymes; however, the ...
An essential component of the ATR (ataxia telangiectasia‐mutated and Rad3‐related)‐activating structure is single‐stranded DNA. It has been suggested that nucleotide excision repair (NER) can lead to ...
Activity of antibody-drug conjugates (ADCs) with radiation in preclinical bladder cancer models. This is an ASCO Meeting Abstract from the 2024 ASCO Genitourinary Cancers Symposium. This abstract does ...
The multiprotein factor composed of XPA and replication protein A (RPA) is an essential subunit of the mammalian nucleotide excision repair system. Although XPA–RPA has been implicated in damage ...
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