There are five major storylines to know heading into the Tennessee Titans vs. San Francisco 49ers Week 15 matchup.

A recharged San Francisco 49ers squad returns from a late season break with renewed momentum as quarterback Brock Purdy ...

The Tennessee Titans face another tough road test against San Francisco this week, and here are five matchups that could ...

A crucial bye week shuffled playoff odds. See how the 49ers climbed without playing, benefiting from rivals' stumbles and ...

NFL Week 15 television maps are out. If you're in blue, you'll see the Tennessee Titans and San Francisco 49ers on your local ...

The San Francisco 49ers are doing so well in 2025 that they probably won't make a pick until later in the first round in the ...

The San Francisco 49ers announced Wednesday that OpenAI chairman Bret Taylor has acquired a minority stake in the team, ...

NFL Week 15 odds, picks, predictions, TV channel, streaming information for the Sunday football game between Tennessee Titans ...

Robert Saleh has been one of the most impressive defensive coordinators in the NFL this season. He is getting by without his ...

The San Francisco 49ers have shared an injury update that could completely change the balance of power in the NFC.

San Francisco coach Kyle Shanahan is focused on preparing for the Tennessee Titans, despite the 49ers being in a prime ...

It's no secret that the San Francisco 49ers are extremely underwhelming with their pass rush. Ever since Nick Bosa was lost ...