Nobody in franchise history — not even all-time NFL touchdown leader Jerry Rice with 208 — has averaged more than a touchdown per game in their first 50 games. In Rice’s first 50 games with the 49ers under Bill Walsh, including the playoffs, he scored 41 touchdowns.

After seeing what Jonathan Taylor did to the Tennessee Titans earlier this year, San Francisco 49ers running back Christian McCaffrey is ready to go to work. The 29-year-old has managed to remain healthy all season as he currently has 1,655 combined yards.

McCaffrey was limited at Thursday's practice due to an illness, David Lombardi of SFStandard.com reports.

Christian McCaffrey and Kyle Shanahan shared why they appreciate the 49ers’ bye week landing during the final stretch of San Francisco's 2025 season.

Preview the player prop betting lines, stats and more for Christian McCaffrey before his San Francisco 49ers play the Tennessee Titans in a Week 15 NFL

Trent Williams aims to help his San Francisco 49ers teammate Christian McCaffrey hit another 1,000-1,000 season in 2025.

TE George Kittle says Christian McCaffrey has "years left in the tank" as the San Francisco star delivers another dominant NFL season.

Here are our leading candidates to win many of the NFL's major awards, which will be unveiled during "NFL Honors" ahead of the Super Bowl.

This year's Thanksgiving was special for Christian McCaffrey and his wife. Olivia Culpo, because of their newborn daughter, Colette.

Christian McCaffrey is making NFL history for the San Francisco 49ers with 1,655 scrimmage yards and top RB receptions through Week 13 of 2025.

Christian McCaffrey and Saquon Barkley lead UPI senior sports writer Alex Butler's Top-50 fantasy football running back rankings for Week 15.