Tumor-Infiltrating Lymphocyte Function Predicts Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Oxaliplatin forms part of routine treatment of advanced colorectal cancer; ...

Nucleotide excision repair (NER) is a major conserved DNA repair pathway, which repairs various types of damage in the genome, such as those induced by ultraviolet light and environmental agents.

Hailin Wang, Meiling Lu, Moon-Shong Tang, Bennett van Houten, J. B. Alexander Ross, Michael Weinfeld, X. Chris Le, Philip C. Hanawalt Proceedings of the National ...

Maintaining the stability of the genome is essential for all organisms, and it is not surprising that damage to DNA has been proposed as an explanation for multiple chronic diseases. 1–5 Conserving a ...

This is a preview. Log in through your library . Abstract We have adapted the eXcision Repair-sequencing (XR-seq) method to generate single-nucleotide resolution dynamic repair maps of UV-induced ...

The Summit supercomputer revealed how damaged strands of DNA are surgically repaired by a molecular pathway called nucleotide excision repair, or NER. NER’s protein components can change shape to ...