Chronic kidney disease (CKD) is characterized by irreversible pathological processes that result in the development of end-stage renal disease (ESRD). Accumulating evidence has emphasized the ...

Tubulointerstitial nephritis is a form of kidney inflammation that affects the microscopic kidney tubules and the interstitial tissue in between them. The result is renal impairment.

Studies investigating what is damaging the kidney in lupus nephritis point to tubulointerstitial inflammation as an important risk factor. Tubulointerstitial inflammation in patients with lupus ...

A recent study posted to medRxiv* preprint server reported a novel form of post-acute coronavirus disease 2019 (COVID-19) syndrome in children. Study: Acute tubulointerstitial nephritis with or ...

This patient presented with advanced renal failure in the setting of severe hypocomplementemia, significant eosinophilia, eosinophiluria, and lymphopenia. He had neither proteinuria nor active urinary ...

Rates of acute kidney injury and tubulointerstitial nephritis associated with anticancer therapy have increased worldwide since 2010, attributable mainly to targeted therapies and immunotherapies.

Tissue remodeling depends on mesenchymal cells (fibroblasts and myofibroblasts) and is a prominent feature of chronic renal-transplant rejection. It is not known whether the mesenchymal cells that ...