Scientists know that TDP-43, which helps regulate processing of RNA, may be responsible for the death of nerve cells in ALS and frontotemporal dementia. And a study suggests that a common modification ...
Two new approaches could help scientists use existing sequencing technology to better-distinguish RNA changes that affect how their genetic code is read Kyoto University scientists are getting closer ...
RNA plays critical roles in nearly all biological processes, but current methods for sequencing RNA are significantly limited. This is partially because RNA molecules are chemically modified within ...
Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message, or mRNA, which is then converted into protein. Although DNA remains the same ...
Osaka, Japan – After a gene is transcribed into RNA, modifications can occur to the subunits or “bases” that make up the RNA molecule, which can affect its structure and function. The study of these ...
A tiny chemical modification commonly found on messenger RNAs plays a surprisingly large role in how cells respond to stress, according to a study led by Weill Cornell Medicine investigators. The ...
A team of researchers has identified a mechanism that causes mitochondrial dysfunction in Alzheimer's patients resulting in a reduction of the supply of energy to the brain. A team of researchers at ...
Compared with eukaryotes, prokaryotes seem very efficient. Their genome is compact, usually consisting of a single chromosome. Most of the DNA encodes proteins. The information content of DNA is ...
Coronavirus disease (COVID-19) hijacks parts of infected cells' vital RNA machinery, thereby blocking important functions in the cells. These damaging changes in the RNA can likely be reversed, ...
The innate immune system is the body's first line of defense against pathogens and foreign substances. An essential component of this system are pattern recognition receptors, which recognize non-self ...
Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message, or mRNA, which is then converted into protein. Although DNA remains the same ...