(SACRAMENTO, Calif.) — The process by which memories are formed in the hippocampus region of the brain is complex. It relies on a precise choreography of interactions between neurons, ...

Mouse neurons stained for enzyme PDE4D5 (green). New work from UC Davis shows that this enzyme plays a key role in memory formation. The process by which memories are formed in the hippocampus region ...

Pyridoxine-dependent epilepsy (PDE) is a rare autosomal recessive epileptic encephalopathy primarily attributed to mutations in the ALDH7A1 gene, which encodes the enzyme antiquitin. Antiquitin plays ...

A new mouse study has identified a gene-enzyme interaction that appears to play a key role in how the brain forms memories. The findings provide insights into how PDE inhibitor medications may help ...