Synthetic hydrogel-based assay to study 3D confined cell migration. Credit: Science Advances (2024). DOI: 10.1126/sciadv.adm9195 Eukaryotic cells—that is, cells with a nucleus—possess an astounding ...

This article won runner-up in our recent writing contest, "What's Your Story?". Congratulations to the author and thanks to everyone who took the time to read the stories and vote. Their tracks were ...

Migrating cells must determine where to form a front end and a back end. A gradient in contact sites between the cell membrane and an organelle called the endoplasmic reticulum (ER) is generated by a ...

Unlike our organs, cell organelles such as mitochondria are not fixed in place, but when, where, how, and why organelles move remain unclear. Research published in the Biophysical Journal shows that ...

The curvature of a surface determines the migration behavior of biological cells. They preferentially move along valleys or grooves while avoiding ridges. These findings gave rise to a model ...

Shootin1b and the adhesion molecule transmit weak traction forces which is well-suited for rapid cell migration, presenting a potential target for preventing spread of glioblastoma. "By suppressing ...

A new Yale-led study has found that stem cells migrate to help repair damaged lung cells caused by injuries such as viral or bacterial infections. The findings were published Feb. 19 in the journal ...

The gastrointestinal tract is the biggest immune organ in mammals. The gut extends its influence all over the body through various links like the gut-liver axis, the gut-lung axis, and the gut-brain ...

Ikoma, Japan—Ever wondered how the different cells in our body communicate with each other to fulfill their different roles—be it cells repairing a tissue injury or immune cells moving towards an ...

How do cells move from A to B through our body to build functional tissues? And how is this process regulated? The answers to these questions are essential – for example, for our understanding of how ...