A vitamin A byproduct has been found to quietly disarm the immune system, allowing tumors to evade attack and weakening ...
Major signaling pathways, including the TGF-β, Wnt/β-catenin, Integrin, and others, are shown to be critical mediators of EMT transcription factors. Glioblastoma (GBM), a malignant tumor originating ...
Figure 1: Key signaling pathways and targeted factors in dysregulated BC. This figure illustrates the major signaling pathways and their intricate crosstalk in BC, focusing on the GPCR, RTKs, ...
The field of cancer immunology has witnessed dramatic progress with the advent of immunotherapies targeting the tumor immune microenvironment (TIME).
Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...
A new study by Scripps Research reveals that alcohol dependence disrupts two signaling pathways in a stress-related part of the brain—and offers insights on developing drugs to treat this condition.
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