Potassium channels can become nonconducting via inactivation at a gate inside the highly conserved selectivity filter (SF) region near the extracellular side of the membrane. In certain ligand-gated ...

For ion transport at nanoscale confinements, a cost of energy is discovered that originates from the rearrangement of the counter-ion shell, with the magnitude of which depending on the type of ...

Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge. Now, researchers have ...

The study, published in Materials Today, details how these membranes could significantly improve energy efficiency and operational stability. Precisely engineered in both pore size and surface ...

The design of new calcium channels, built bottom-up from scratch, was reported last week in Nature. Subscribe to our newsletter for the latest sci-tech news updates. Ion channels generate electrical ...

Pretein design researcher Yulai Liu holds an enlarged 3D printed model from his team's efforts to design functioning calcium channels entirely from scratch. He is standing in David Baker's lab at the ...