Toward the goal of generating high-quality embryo models in vitro, this study establishes a stepwise protocol to derive trophectoderm-like cells from mouse extended pluripotent stem (EPS) cells. These ...

Only two weeks after fertilization, the first sign of the formation of the three axes of the human body (head/tail, ventral/dorsal, and right/left) begins to appear. At this stage, known as ...

A small tissue fold in fly embryos, once thought purposeless, plays a vital role in stabilizing tissues. Researchers show that it absorbs stress during early development, and its position and timing ...

A cell aggregation of human pluripotent stem cells and amniotic ectoderm cells generated by the published culture method and mimicking the gastrulation event in human embryos. Gray: nuclei, Cyan: ...

Researchers have developed a theoretical framework that can reproduce and predict the patterns associated with gastrulation in a chicken embryo. Gastrulation is one of the most important phases in ...

Only two weeks after fertilization, the first sign of the formation of the 3 axes of the human body (head/tail, ventral/dorsal, and right/left) begins to appear. At this stage, known as gastrulation, ...

Researchers at UCL and the Francis Crick Institute have, for the first time, identified the origin of cardiac cells using 3D images of a heart forming in real-time, inside a living mouse embryo. For ...