Until today, skin, brain, and all tissues of the human body were difficult to observe in detail with an optical microscope, since the contrast in the image was hindered by the high density of their ...

Researchers have developed a groundbreaking microscopy method that enables detailed three-dimensional (3D) RNA analysis at cellular resolution in whole intact mouse brains. The new method, called ...

Scientists have unveiled the most detailed map of the brain ever created. The fascinating chart represents almost 10 million neurons, 26 billion synapses and 86 interconnected brain regions. It was ...

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As millions of Americans adjust their clocks for daylight saving time this week, many experience disruptions in their sleep and daily routines – a reminder of the importance of circadian rhythms that ...

Biophysically detailed simulation of the whole mouse cortex neuron by neuron, with sub-cellular resolution—that is, capturing ion flows and fluctuations of membrane voltage within many compartments ...

In 1979, biologist Francis Crick claimed it would be impossible to create an accurate diagram of the brain’s wiring and neuronal activity—even within just a cubic millimeter of brain tissue. Now, a ...

Mapping all the connections among the brain’s 100 billion neurons is one of the great scientific and engineering challenges of our time. Scientists, including those at the University of Chicago, began ...