Here, we investigated the complement binding of necrotic and apoptotic cells in different states of cell death. To induce necrosis of polymorphonuclear cells (PMN) and of peripheral blood lymphocytes ...
For this study, we generated human fH-derived recombinant SCR18–20 (hSCR18–20), representing a main binding domain of fH. Here, we show that by replacing fH from the surface of primary CLL cells with ...
Antibodies play an important role in the immune system. The immunoglobulins present on the B-lymphocyte surface send in signals to the cytoplasmic and nuclear electors. These also deliver the antigen ...