CRISPR, short for Clustered Regularly Interspaced Short Palindromic Repeats, is a revolutionary gene-editing tool originally discovered as a bacterial defence mechanism. Scientists have repurposed it ...
CRISPR’s promise of curing diseases hit a setback when researchers discovered that AZD7648, a molecule designed to improve precision, also caused catastrophic hidden damage to DNA. Instead of perfect ...
In December 2020, the New England Journal of Medicine published a paper titled CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia, marking an exciting new chapter in the treatment of ...
Since its discovery in 2011, CRISPR-Cas 9 has revolutionized medicine. One of the companies at the forefront of this revolution is CRISPR Therapeutics. Map shows Donald Trump's approval rating in each ...
**Note: the release below is a special early release from the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024, Barcelona, Spain, 27-30 April). Please credit the ...
Gene editing in plants remains challenging, with the traditional non-homologous end-joining (cNHEJ) repair pathway often hindering precision. In this study, researchers advanced CRISPR-Cas-based gene ...
In an extraordinary 6,000-word guest editorial in the October 2024 issue of The CRISPR Journal (a sister journal of GEN, published by Mary Ann Liebert, Inc.), Fyodor Urnov, PhD, laid out the urgent ...
The gene editing technique CRISPR/Cas9 has allowed researchers to make precise and impactful changes to an organism's DNA to fix mutations that cause genetic disease. However, the CRISPR/Cas9 method ...