Raman imaging and scanning electron microscopy (SEM) was used to investigate acetaminophen solid dispersions prepared by hot melt extrusion (HME). This experiment confirmed that a high screw speed ...

Spray-drying is a preferred process for manufacturing amorphous solid dispersions, which provide oral bioavailability enhancement for low-solubility small molecules. High permeability, low-solubility ...

Low solubility and bioavailability challenges are prevalent, necessitating early selection of appropriate drug delivery technologies to optimize clinical and commercial success. Amorphous solid ...

(Nanowerk News) Glass, rubber and plastics all belong to a class of matter called amorphous solids. And in spite of how common they are in our everyday lives, amorphous solids have long posed a ...

In industrial production, the surface of the compound may become amorphous due to a small amount of structural damage. It is difficult for conventional instruments to detect this small amount of ...

For more than a century, an important class of matter -- the amorphous solid -- has eluded scientists' ability to depict nature at the level of atoms and molecules. Until now. A new study reports the ...